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Friday, 1 April 2011

Neoplastic Diseases in Poultry MYELOCYTOMATOSIS

Neoplastic Diseases in Poultry

MYELOCYTOMATOSIS

311 312 311.312.MC is caused by viral staings of ALSVs from sungroups A,B and J (Mc29, MC31, Cm11, OK10, HRPS 103, and ADOL HC1). It is encountered relatively infrequently. Its occurrence is sporadic or enzootic. Suceptible birds and hens, pheasents, guinea hens and quails. In most cases, the liver is enlarged, thick and mottled with dark red sports or fat like nodules.
 
313 314 313.314.. MC is caused by viral strains of ALSVs from subgroups A, B and J (MC29, MC31, CMII, OK10, HRPS 103, and ADOL HC1). It is encountered relatively infrequently. Its occurrence is sporadic or enzootic. Susceptible birds are hens, pheasants, guinea hens and quails. In most cases, the liver is enlarged, thick and mottled with dark red spots or fat-like nodules.
 
315 315.Sclerotic changes in the liver are possible because of regression of neoplastic lesions.
 
316 316.The spleen is usually enlarged, but sometimes, could be atrophied.
 
317 317.. A characteristic feature of MC is its simultaneous course with tumours from a different type: mesenchymal, epithelial or mixed. The picture shows a fibrosarcoma to the gizzard associated with MC.
 
318 318.Mixed mesenchymal tumour (osteochondrosarcoma) to the frontal skull bones: a sagittal cross section
 
319 319.Multiple rabdomyosarcoma in pectoral, thigh, abdominal and tracheal muscles.
 
320 320.Leiomyosarcoma of the mucous coat on the oviduct.
 
321 321.Pendulation harmangio-sarcoma of the ileal serosa.
 
322 322.Pendulating multiple myxoma of the small intestine's serous coat.
 
323 323.. MC-associated cystadenocarcinoma of the kidney in a hen.
 
324 324.Nephroblastoma of the left kidney, occupying a significant part of the abdominal cavity.
 
325 325.Nephroblastoma -the surface of a cross section. The tumour is a pendulating mass attached to the kidney by a fibrous vascularized stem that has undergone a partial necrosis and haemorrhages
 
326 326.Granulosa cell tumour of the ovary. The tumour appears as a single, compact, dorsoventrally flattened growth.
 
327 327.MC-associated multiple carcino¬sarcoma of the mesentery and alimentary tract's serous coat (disseminated milliary nodules).
 
328 328.MC-associated carcinosarcomas in the region of the right infraorbital sinus.
 
329 329.Gross appearance of the tumour from Fig. 328 after removal of the covering skin.
 
330 330.Histologically, myelocytomatomas are easily distinguished. Most commonly, they have perivascular localization. Growth of myelocytes with well-formed granules in a liver cross-section.
 
331 331.Kidney.Focal intertubular myelocytic pro¬liferations.
 
332 332.. MC-associated neoplasms of epithelial, mesenchymal or mixed type demonstrate the respective type of histological structure. Leiomyosarcoma a histological view. Polygonal giant cells with hyperchromatic nuclei.
 
333 333.Leiomyosarcoma - small intestime. Prolongations of polynuclear symplastic elements.
 
334 334.Leiomyosarcoma - small intestine. Extraordinary („monstrous") multinuclear giant cell with intracytoplasmic vacuoles.
 
335 335.. Rabdomyosarcoma. An area with multiple hyperchromatic giant cells.
 
336. 336.Carcinosarcoma of the pancreas. Tubulous glandular epithelial formations of the carcinoma component among the liposarcoma part of the parenchyma. The diagnosis is based upon the entity of data about the history, the gross appearance and location of the tumours and the specific histo¬logical lesions. From a differential diagnostic point of view, myelo¬blastosis and erythroblastosis should be considered.

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